COPS2 anticorps

N° du produit ABIN2461718

L’anticorps anti-COPS2 Polyclonal Lapin est utilisé pour la détection de COPS2 dans des échantillons de Humain, Souris, Rat, Chien et Poisson zèbre (Danio rerio). Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour COPS2 anticorps (ABIN2461718)

Antigène: COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-COPS2 anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COPS2.

Information d'application

Indications d'application: COPS2 antibody can be used for detection of COPS2 by ELISA at 1:312500. COPS2 antibody can be used for detection of COPS2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store COPS2 antibody at -20 °C.

Détails sur COPS2

Antigène: COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))

Autre désignation: COPS2

Sujet: COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.

Poids moléculaire: 51 kDa

ID gène: 9318

NCBI Accession: NP_004227

UniProt: P61203

Pathways: Cycle Cellulaire