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RGS18 anticorps

RGS18 Reactivité: Humain, Chien ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2462635
  • Antigène Voir toutes RGS18 Anticorps
    RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
    Reactivité
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Chien
    Hôte
    • 10
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 13
    • 1
    Polyclonal
    Conjugué
    • 10
    • 2
    • 1
    • 1
    Cet anticorp RGS18 est non-conjugé
    Application
    • 9
    • 6
    • 2
    • 1
    ELISA, Western Blotting (WB)
    Purification
    Antibody is purified by protein A chromatography method.
    Immunogène
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RGS18.
    Top Product
    Discover our top product RGS18 Anticorps primaire
  • Indications d'application
    RGS18 antibody can be used for detection of RGS18 by ELISA at 1:62500. RGS18 antibody can be used for detection of RGS18 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Conseil sur la manipulation
    As with any antibody avoid repeat freeze-thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store RGS18 antibody at -20 °C.
  • Antigène
    RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
    Autre désignation
    RGS18 (RGS18 Produits)
    Synonymes
    anticorps RGS18, anticorps rgs18, anticorps RGS13, anticorps regulator of G-protein signaling 18, anticorps regulator of G protein signaling 18, anticorps RGS18, anticorps rgs18, anticorps LOC100224724, anticorps Rgs18
    Sujet
    RGS18 is a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
    Poids moléculaire
    26 kDa
    ID gène
    64407
    NCBI Accession
    NP_570138
    UniProt
    Q9NS28
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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