DTX2 anticorps

N° du produit ABIN2462679

Cet anticorps anti-DTX2 est un anticorps Lapin Polyclonal détectant DTX2 dans WB et ELISA. Adapté pour Humain, Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour DTX2 anticorps (ABIN2462679)

Antigène: DTX2 (Deltex Homolog 2 (DTX2))

Reactivité: Humain, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DTX2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DTX2 anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DTX2.

Information d'application

Indications d'application: DTX2 antibody can be used for detection of DTX2 by ELISA at 1:312500. DTX2 antibody can be used for detection of DTX2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DTX2 antibody at -20 °C.

Détails sur DTX2

Antigène: DTX2 (Deltex Homolog 2 (DTX2))

Autre désignation: DTX2

Sujet: DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Poids moléculaire: 62 kDa, 67 kDa, 67 kDa, 67 kDa, 93 kDa, 26 kDa, 93 kDa, 45 kDa

ID gène: 113878

NCBI Accession: NP_001096066

UniProt: Q6XM87

Pathways: Signalisation Notch