DTX2 anticorps

N° du produit ABIN2462679

Détail du produit anti-DTX2 anticorps

Antigène: DTX2 (Deltex Homolog 2 (DTX2))

Reactivité: Humain, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DTX2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DTX2.

Information d'application

Indications d'application: DTX2 antibody can be used for detection of DTX2 by ELISA at 1:312500. DTX2 antibody can be used for detection of DTX2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DTX2 antibody at -20 °C.

Détails sur DTX2

Antigène: DTX2 (Deltex Homolog 2 (DTX2))

Autre désignation: DTX2 (DTX2 Produits)

Synonymes: anticorps RNF58, anticorps 2610524D08Rik, anticorps AA408415, anticorps AU022494, anticorps Deltex2, anticorps dtx2, anticorps deltex E3 ubiquitin ligase 2, anticorps probable E3 ubiquitin-protein ligase DTX2, anticorps deltex 2, E3 ubiquitin ligase, anticorps deltex 2, E3 ubiquitin ligase S homeolog, anticorps DTX2, anticorps Dtx2, anticorps LOC735784, anticorps LOC747633, anticorps dtx2, anticorps dtx2.S

Sujet: DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Poids moléculaire: 62 kDa, 67 kDa, 67 kDa, 67 kDa, 93 kDa, 26 kDa, 93 kDa, 45 kDa

ID gène: 113878

NCBI Accession: NP_001096066

UniProt: Q6XM87

Pathways: Signalisation Notch