Cadherin 7 anticorps

N° du produit ABIN2462981

Détail du produit anti-Cadherin 7 anticorps

Antigène: Cadherin 7 (CDH7)

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 7 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDH7.

Information d'application

Indications d'application: CDH7 antibody can be used for detection of CDH7 by ELISA at 1:12500. CDH7 antibody can be used for detection of CDH7 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CDH7 antibody at -20 °C.

Détails sur Cadherin 7

Antigène: Cadherin 7 (CDH7)

Autre désignation: CDH7 (CDH7 Produits)

Synonymes: anticorps CDH7L1, anticorps Cad7, anticorps 9330156F07Rik, anticorps cadherin 7, anticorps cadherin 7, type 2, anticorps cadherin 7a, anticorps CDH7, anticorps Cdh7, anticorps cdh7a

Sujet: CDH7 is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures.This gene is a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures. Alternative splicing in the 5' UTR of this gene yields variant transcripts encoding the same protein.

Poids moléculaire: 82 kDa, 88 kDa, 88 kDa, 89 kDa, 87 kDa

ID gène: 1005

NCBI Accession: NP_004352

UniProt: Q9ULB5

Pathways: Cell-Cell Junction Organization