POLR3B anticorps

N° du produit ABIN2463219

Détail du produit anti-POLR3B anticorps

Antigène: POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))

Reactivité: Humain, Souris, Rat, Drosophila melanogaster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR3B est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POLR3B.

Information d'application

Indications d'application: POLR3B antibody can be used for detection of POLR3B by ELISA at 1:12500. POLR3B antibody can be used for detection of POLR3B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store POLR3B antibody at -20 °C.

Détails sur POLR3B

Antigène: POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))

Autre désignation: POLR3B (POLR3B Produits)

Synonymes: anticorps RGD1565311, anticorps C128, anticorps HLD8, anticorps RPC2, anticorps 2700078H01Rik, anticorps A330032P03Rik, anticorps C85372, anticorps RNA polymerase III subunit B, anticorps polymerase (RNA) III (DNA directed) polypeptide B, anticorps Polr3b, anticorps POLR3B

Sujet: POLR3B belongs to the RNA polymerase beta chain family. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3B is the second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

Poids moléculaire: 128 kDa

ID gène: 55703

NCBI Accession: NP_060552

UniProt: Q9NW08