NAGS anticorps

N° du produit ABIN2463410

L’anticorps Lapin Polyclonal anti-NAGS a été validé pour WB et ELISA. Il convient pour détecter NAGS dans des échantillons de Humain, Souris, Rat et Chien.

Aperçu rapide pour NAGS anticorps (ABIN2463410)

Antigène: NAGS (N-Acetylglutamate Synthase (NAGS))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAGS est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NAGS anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NAGS.

Information d'application

Indications d'application: NAGS antibody can be used for detection of NAGS by ELISA at 1:312500. NAGS antibody can be used for detection of NAGS by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NAGS antibody at -20 °C.

Détails sur NAGS

Antigène: NAGS (N-Acetylglutamate Synthase (NAGS))

Autre désignation: NAGS

Sujet: NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.

Poids moléculaire: 58 kDa

ID gène: 162417

NCBI Accession: NP_694551

UniProt: Q8N159