CHRNB3 anticorps

N° du produit ABIN2463734

L’anticorps Lapin Polyclonal anti-CHRNB3 a été validé pour WB et ELISA. Il convient pour détecter CHRNB3 dans des échantillons de Humain, Souris, Rat et Chien.

Aperçu rapide pour CHRNB3 anticorps (ABIN2463734)

Antigène: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNB3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CHRNB3 anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRNB3.

Information d'application

Indications d'application: CHRNB3 antibody can be used for detection of CHRNB3 by ELISA at 1:1562500. CHRNB3 antibody can be used for detection of CHRNB3 by western blot at 0.03 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CHRNB3 antibody at -20 °C.

Détails sur CHRNB3

Antigène: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Autre désignation: CHRNB3

Sujet: Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels nAChRs are pentameric structures that are made up of combinations of individual subunits. CHRNB3 is one of the subunits of nAChR. Twelve neuronal nAChR subunits have been described, alpha2-alpha10 and beta2-beta4. CHRNB3 decreased the channel mean open time and burst length. There was also an increase in single channel slope conductance. On the other hand, the calcium permeability and the pharmacological properties of beta3-containing receptors differed little from those of without beta3. Dysfunction of nAChR has been linked to a number of human diseases such as schizophrenia, Alzheimer's and Parkinson's diseases. nAChRs also play a significant role in nicotine addiction.

Poids moléculaire: 53 kDa

ID gène: 1142

NCBI Accession: NP_000740

UniProt: Q05901