CHRNB3 anticorps (Middle Region)

N° du produit ABIN926966

Détail du produit anti-CHRNB3 anticorps

Antigène: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNB3 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus), Chien, Poulet, Grenouille

Purification: Purified

Immunogène: CHRNB3 antibody was raised in rabbit using the middle region of CHRNB3 as the immunogen

Information d'application

Indications d'application: WB: 0.03 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CHRNB3 Blocking Peptide, catalog no. 33R-10069, is also available for use as a blocking control in assays to test for specificity of this CHRNB3 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur CHRNB3

Antigène: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Autre désignation: CHRNB3 (CHRNB3 Produits)

Synonymes: anticorps 5730417K16Rik, anticorps Acrb3, anticorps NACHR, anticorps CHRNB3, anticorps chrnb3, anticorps cholinergic receptor nicotinic beta 3 subunit, anticorps neuronal acetylcholine receptor subunit beta-3, anticorps cholinergic receptor, nicotinic, beta polypeptide 3, anticorps cholinergic receptor, nicotinic beta 3 L homeolog, anticorps cholinergic receptor, nicotinic beta 3, anticorps cholinergic receptor, nicotinic, beta 3b (neuronal), anticorps cholinergic receptor, nicotinic, beta polypeptide 3a, anticorps CHRNB3, anticorps CpipJ_CPIJ012638, anticorps Chrnb3, anticorps chrnb3.L, anticorps chrnb3, anticorps chrnb3b, anticorps chrnb3a

Sujet: Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels nAChRs are pentameric structures that are made up of combinations of individual subunits. CHRNB3 is one of the subunits of nAChR. Twelve neuronal nAChR subunits have been described, alpha2-alpha10 and beta2-beta4. CHRNB3 decreased the channel mean open time and burst length. There was also an increase in single channel slope conductance. On the other hand, the calcium permeability and the pharmacological properties of beta3-containing receptors differed little from those of without beta3. Dysfunction of nAChR has been linked to a number of human diseases such as schizophrenia, Alzheimer's and Parkinson's diseases. nAChRs also play a significant role in nicotine addiction. Synonyms: Polyclonal CHRNB3 antibody, Anti-CHRNB3 antibody, cholinergic receptor, nicotinic, beta 3 antibody.