CHRNB3 anticorps

N° du produit ABIN2463734

Détail du produit anti-CHRNB3 anticorps

Antigène: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNB3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRNB3.

Information d'application

Indications d'application: CHRNB3 antibody can be used for detection of CHRNB3 by ELISA at 1:1562500. CHRNB3 antibody can be used for detection of CHRNB3 by western blot at 0.03 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CHRNB3 antibody at -20 °C.

Détails sur CHRNB3

Antigène: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Autre désignation: CHRNB3 (CHRNB3 Produits)

Synonymes: anticorps 5730417K16Rik, anticorps Acrb3, anticorps NACHR, anticorps CHRNB3, anticorps chrnb3, anticorps cholinergic receptor nicotinic beta 3 subunit, anticorps neuronal acetylcholine receptor subunit beta-3, anticorps cholinergic receptor, nicotinic, beta polypeptide 3, anticorps cholinergic receptor, nicotinic beta 3 L homeolog, anticorps cholinergic receptor, nicotinic beta 3, anticorps cholinergic receptor, nicotinic, beta 3b (neuronal), anticorps cholinergic receptor, nicotinic, beta polypeptide 3a, anticorps CHRNB3, anticorps CpipJ_CPIJ012638, anticorps Chrnb3, anticorps chrnb3.L, anticorps chrnb3, anticorps chrnb3b, anticorps chrnb3a

Sujet: Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels nAChRs are pentameric structures that are made up of combinations of individual subunits. CHRNB3 is one of the subunits of nAChR. Twelve neuronal nAChR subunits have been described, alpha2-alpha10 and beta2-beta4. CHRNB3 decreased the channel mean open time and burst length. There was also an increase in single channel slope conductance. On the other hand, the calcium permeability and the pharmacological properties of beta3-containing receptors differed little from those of without beta3. Dysfunction of nAChR has been linked to a number of human diseases such as schizophrenia, Alzheimer's and Parkinson's diseases. nAChRs also play a significant role in nicotine addiction.

Poids moléculaire: 53 kDa

ID gène: 1142

NCBI Accession: NP_000740

UniProt: Q05901