APOA5 anticorps (truncated)

N° du produit ABIN2464012

Détail du produit anti-APOA5 anticorps

Antigène: APOA5 (Apolipoprotein A-V (APOA5))

Épitope: truncated

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp APOA5 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: Ni-NTA purified truncated recombinant human APOA5 expressed in E. Coli strain BL21 (DE3).

Clone: 4H8H8E2(c)

Isotype: IgG1

Information d'application

Indications d'application: Western Blot, ELISA.
Dilution:
Western Blot:1:500 - 1,000
ELISA:Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: -20 °C

Stockage commentaire: Apoa5(bd) monoclonal antibody can be stored at -20 °C, stable for one year.

Détails sur APOA5

Antigène: APOA5 (Apolipoprotein A-V (APOA5))

Autre désignation: Apoa5 (APOA5 Produits)

Synonymes: anticorps APOAV, anticorps RAP3, anticorps 1300007O05Rik, anticorps Apoav, anticorps apo-AV, anticorps apoA-V, anticorps APOA5, anticorps MGC140487, anticorps rap3, anticorps apoav, anticorps apoa-v, anticorps apolipoprotein A5, anticorps apolipoprotein A-V, anticorps apolipoprotein A5 L homeolog, anticorps APOA5, anticorps Apoa5, anticorps apoa5.L, anticorps apoa5

Sujet: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglyc erides, whereas a knock-in model with human ApoA5 produced 50 70 % lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.

ID gène: 116519

UniProt: Q6Q788

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism