Aurora Kinase B anticorps (truncated)

N° du produit ABIN2464014

Cet anticorps anti-Aurora Kinase B Monoclonal Souris (Clone 13E8D3) (ABIN2464014) détecte spécifiquement Aurora Kinase B dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Aurora Kinase B anticorps (truncated) (ABIN2464014)

Antigène: Aurora Kinase B (AURKB)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Aurora Kinase B est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 13E8D3

Détail du produit anti-Aurora Kinase B anticorps

Épitope: truncated

Immunogène: Ni-NTA purified truncated recombinant AURKB expressed in E. Coli strain BL21 (DE3).

Isotype: IgG1

Information d'application

Indications d'application: Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: -20 °C

Stockage commentaire: AURKB monoclonal antibody can be stored at -20 °C, stable for one year.

Détails sur Aurora Kinase B

Antigène: Aurora Kinase B (AURKB)

Autre désignation: AURKB

Sujet: AURKB (aurora kinase B, AIK2 or aurora-B), with 344-amino acid protein(about 39 kDa),localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. AURKB is a mitotic protein kinase, which phosphorylates histone H3 and regulates Chromosomal segregation during mitosis and meiosis.It may regulates several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis.Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. ARK-2 transcripts arepresent at high levels in human thymus and fetal liver.ARK-2 protein levels are maximal during both S and G2/M phases

ID gène: 9212

UniProt: Q96GD4

Pathways: TCR Signaling, Cycle Cellulaire, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades