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Aurora Kinase B anticorps (truncated)
AURKB
Reactivité: Humain
WB, ELISA
Hôte: Souris
Monoclonal
13E8D3
unconjugated
N° du produit ABIN2464014
Détail du produit anti-Aurora Kinase B anticorps
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Antigène
Voir toutes Aurora Kinase B (AURKB) Anticorps
Aurora Kinase B (AURKB)
Épitope
Tous les épitopes à travers Aurora Kinase B Anticorps.
truncated
Reactivité
Toutes les réactivités sur Aurora Kinase B Anticorps
Humain
Hôte
Toutes les hôtes sur Aurora Kinase B Anticorps
Souris
Clonalité
Toutes les clonalités sur Aurora Kinase B Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers Aurora Kinase B Anticorps
Cet anticorp Aurora Kinase B est non-conjugé
Application
Tous les applications à travers Aurora Kinase B Anticorps.
Western Blotting (WB), ELISA
Immunogène
Ni-NTA purified truncated recombinant AURKB expressed in E. Coli strain BL21 (DE3).
Clone
13E8D3
Isotype
IgG1
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Information d'application
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Indications d'application
Western Blot:1:500 - 1:2,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Stock
-20 °C
Stockage commentaire
AURKB monoclonal antibody can be stored at -20 °C, stable for one year.
Détails sur Aurora Kinase B
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Antigène
Aurora Kinase B (AURKB)
Autre désignation
AURKB (AURKB Produits )
Synonymes
anticorps AIK2, anticorps AIM-1, anticorps AIM1, anticorps ARK2, anticorps AurB, anticorps IPL1, anticorps PPP1R48, anticorps STK12, anticorps STK5, anticorps aurkb-sv1, anticorps aurkb-sv2, anticorps AIRK2, anticorps AL022959, anticorps Aik2, anticorps Aim1, anticorps Ark2, anticorps STK-1, anticorps Stk12, anticorps Stk5, anticorps Aur B, anticorps Aurora B, anticorps Aurora-B, anticorps CG6620, anticorps DmAIRK2, anticorps DmAurB, anticorps DmAuroraB, anticorps Dmel\\CG6620, anticorps IAL, anticorps IAL1, anticorps Ial, anticorps aurB, anticorps aurora B, anticorps ARK-2, anticorps XAIRK2, anticorps aik2, anticorps aim-1, anticorps aim1, anticorps airk2, anticorps ark2, anticorps ipl1, anticorps stk12, anticorps stk5, anticorps CHUNP6896, anticorps fa09g06, anticorps stka, anticorps wu:fa09g06, anticorps aurkb, anticorps AIRK2-B, anticorps XAIRK2-B, anticorps aurkb-a, anticorps aurkb-b, anticorps xAurora-B-B, anticorps aurora kinase B, anticorps aurora B, anticorps aurora kinase B S homeolog, anticorps AURKB, anticorps Aurkb, anticorps aurB, anticorps aurkb, anticorps aurkb.S
Sujet
AURKB (aurora kinase B, AIK2 or aurora-B), with 344-amino acid protein(about 39 kDa),localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. AURKB is a mitotic protein kinase, which phosphorylates histone H3 and regulates Chromosomal segregation during mitosis and meiosis.It may regulates several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis.Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. ARK-2 transcripts arepresent at high levels in human thymus and fetal liver.ARK-2 protein levels are maximal during both S and G2/M phases
ID gène
9212
UniProt
Q96GD4
Pathways
TCR Signaling , Cycle Cellulaire , Maintenance of Protein Location , Hepatitis C , Toll-Like Receptors Cascades
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