BLK anticorps (truncated)

N° du produit ABIN2464016

Détail du produit anti-BLK anticorps

Antigène: BLK (B Lymphoid Tyrosine Kinase (BLK))

Épitope: truncated

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BLK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogène: Ni-NTA purified truncated recombinant BLK expressed in E. Coli strain BL21 (DE3).

Clone: 9D10D1

Isotype: IgG2a

Information d'application

Indications d'application: Western Blot:1:500 - 1:2,000
IHC(P)1:500 - 1:2,000
IHC(F)1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: -20 °C

Stockage commentaire: BLK monoclonal antibody can be stored at -20 °C, stable for one year.

Détails sur BLK

Antigène: BLK (B Lymphoid Tyrosine Kinase (BLK))

Autre désignation: BLK (BLK Produits)

Synonymes: anticorps bltk, anticorps si:dkey-33i22.2, anticorps zgc:136231, anticorps MODY11, anticorps BLK proto-oncogene, Src family tyrosine kinase, anticorps B lymphoid kinase, anticorps blk, anticorps BLK, anticorps Blk

Sujet: BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56 kDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

ID gène: 640

UniProt: P51451

Pathways: Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling