KIT anticorps (truncated)

N° du produit ABIN2464038

Détail du produit anti-KIT anticorps

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Épitope: truncated

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KIT est non-conjugé

Application: ELISA

Purification: Antibody is purified by protein A affinity chromatography.

Immunogène: Ni-NTA purified truncated recombinant C-kit expressed in E. Coli strain BL21 (DE3).

Clone: 8D7B4-8D7D4-7H6B2-7H6B12

Isotype: IgG1

Information d'application

Indications d'application: Dilution
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: -20 °C

Stockage commentaire: C-Kit monoclonal antibody can be stored at -20 °C, stable for one year.

Détails sur KIT

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Autre désignation: CKit (KIT Produits)

Synonymes: anticorps C-Kit, anticorps CD117, anticorps PBT, anticorps SCFR, anticorps Bs, anticorps Fdc, anticorps Gsfsco1, anticorps Gsfsco5, anticorps Gsfsow3, anticorps SCO1, anticorps SCO5, anticorps SOW3, anticorps Ssm, anticorps Tr-kit, anticorps W, anticorps c-KIT, anticorps c-kit, anticorps MGF, anticorps KIT, anticorps C-KIT, anticorps kit, anticorps receptor, anticorps sparse, anticorps Xkl-1, anticorps kit-a, anticorps kit-b, anticorps kl1-A, anticorps krk1, anticorps pbt, anticorps scfr, anticorps KIT proto-oncogene receptor tyrosine kinase, anticorps v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a, anticorps KIT proto-oncogene receptor tyrosine kinase S homeolog, anticorps KIT, anticorps Kit, anticorps kita, anticorps kit, anticorps kit.S

Sujet: C-kit (CD117,145 kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

ID gène: 3815

UniProt: P10721

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity