Survivin anticorps (full length)

N° du produit ABIN2464110

Cet anticorps anti-Survivin Monoclonal Souris (Clone 2H5H2) (ABIN2464110) détecte spécifiquement Survivin dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Survivin anticorps (full length) (ABIN2464110)

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Survivin est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 2H5H2

Détail du produit anti-Survivin anticorps

Épitope: full length

Immunogène: Purified full-length recombinant Survivin-His is expressed in E.Coli strain BL21 (DE3).The antigen is soluble.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: -20 °C

Stockage commentaire: Survivin monoclonal antibody can be stored at -20 °C, stable for one year.

Détails sur Survivin

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Autre désignation: Survivin

Sujet: Baculoviral IAP repeat-containing 5 (survivin).This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.

ID gène: 332

UniProt: O15392

Pathways: Apoptose, Cycle Cellulaire, Nuclear Hormone Receptor Binding