C3 anticorps

N° du produit ABIN2467785

Cet anticorps anti-C3 est un anticorps Poulet Polyclonal détectant C3 dans ELISA. Adapté pour Humain.

Aperçu rapide pour C3 anticorps (ABIN2467785)

Antigène: C3 (Complement Component 3 (C3))

Reactivité: Humain

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp C3 est non-conjugé

Application: ELISA

Détail du produit anti-C3 anticorps

Purification: Antigen affinity-purified

Immunogène: plasma protein

Information d'application

Indications d'application: C3 antibody can be used for the detection of C3 by Western blot, ELISA, may also work for IHC and ICC.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Agent conservateur: Without preservative

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Stockage commentaire: C3 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Détails sur C3

Antigène: C3 (Complement Component 3 (C3))

Autre désignation: Complement Component C3

Sujet: Human complement component C3. Complement C3 contains two chains linked by a disulfide bond. Its activation by a C3 convertase releases the C3a anaphylatoxin from the amino end of the alpha chain and generates C3b, which associates with the Bb fragment of complement factor B to form the alternative-complement-pathway C3/C5 convertase.C3a anaphylatoxin is a vasoactive peptide and a mediator of inflammation. C3b, with its highly reactive thiol group, binds to the surface of foreign particles and facilitates phagocytosis. It binds to complement C5 and renders it susceptible to proteolysis by the classical-complement-pathway C3/C5 convertase. The activity of C3b is regulated by proteolytic cleavage involving factors H and I. Its degradation products can also be biologically active.

Poids moléculaire: 187.2 kDa (calculated)

ID gène: 718

NCBI Accession: NP_000055

UniProt: P01024

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling