C3 anticorps
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- Antigène Voir toutes C3 Anticorps
- C3 (Complement Component 3 (C3))
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Reactivité
- Humain
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Hôte
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Poulet
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp C3 est non-conjugé
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Application
- ELISA
- Purification
- Antigen affinity-purified
- Immunogène
- plasma protein
- Top Product
- Discover our top product C3 Anticorps primaire
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- Indications d'application
- C3 antibody can be used for the detection of C3 by Western blot, ELISA, may also work for IHC and ICC.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate-Buffered Saline. No preservatives added.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- C3 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- Antigène
- C3 (Complement Component 3 (C3))
- Autre désignation
- Complement Component C3 (C3 Produits)
- Synonymes
- anticorps AHUS5, anticorps ARMD9, anticorps ASP, anticorps C3a, anticorps C3b, anticorps CPAMD1, anticorps AI255234, anticorps HSE-MSF, anticorps Plp, anticorps C3, anticorps C3-1, anticorps sb:cb26, anticorps si:dkey-76b14.4, anticorps wu:fi34b03, anticorps wu:fj86e11, anticorps C3d, anticorps asp, anticorps cpamd1, anticorps c3, anticorps complement C3, anticorps complement component 3, anticorps complement component c3a, duplicate 1, anticorps complement component 3 L homeolog, anticorps complement component C3, anticorps complement C3-like, anticorps C3, anticorps c3a.1, anticorps c3.L, anticorps LOC443475, anticorps c3, anticorps c3-1, anticorps LOC100060539
- Sujet
- Human complement component C3. Complement C3 contains two chains linked by a disulfide bond. Its activation by a C3 convertase releases the C3a anaphylatoxin from the amino end of the alpha chain and generates C3b, which associates with the Bb fragment of complement factor B to form the alternative-complement-pathway C3/C5 convertase.C3a anaphylatoxin is a vasoactive peptide and a mediator of inflammation. C3b, with its highly reactive thiol group, binds to the surface of foreign particles and facilitates phagocytosis. It binds to complement C5 and renders it susceptible to proteolysis by the classical-complement-pathway C3/C5 convertase. The activity of C3b is regulated by proteolytic cleavage involving factors H and I. Its degradation products can also be biologically active.
- Poids moléculaire
- 187.2 kDa (calculated)
- ID gène
- 718
- NCBI Accession
- NP_000055
- UniProt
- P01024
- Pathways
- Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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