PDE9A anticorps (Internal Region)

N° du produit ABIN2469457

Cet anticorps Lapin Polyclonal détecte spécifiquement PDE9A dans IHC. Il présente une réactivité envers Humain, Chien, Singe et Gibbon.

Aperçu rapide pour PDE9A anticorps (Internal Region) (ABIN2469457)

Antigène: PDE9A (phosphodiesterase 9A (PDE9A))

Reactivité: Humain, Chien, Singe, Gibbon

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE9A est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-PDE9A anticorps

Épitope: Internal Region

Specificité: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogène: PDE9A antibody was raised against a peptide located near the internal domain of PDE9A (Human).

Information d'application

Indications d'application: PDE9A antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-80 °C

Stockage commentaire: PDE9A antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Détails sur PDE9A

Antigène: PDE9A (phosphodiesterase 9A (PDE9A))

Autre désignation: PDE9A

Sujet: Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.

ID gène: 5152

UniProt: O76083