Connexin 43/GJA1 anticorps (C-Term)

N° du produit ABIN2469543

Cet anticorps anti-Connexin 43/GJA1 est un anticorps Lapin Polyclonal détectant Connexin 43/GJA1 dans IHC. Adapté pour Humain, Rat, Souris, Chien, Boeuf (Vache), Singe, Lapin, Cobaye, Porc, Hamster, Gibbon et Gorilla.

Aperçu rapide pour Connexin 43/GJA1 anticorps (C-Term) (ABIN2469543)

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Singe, Lapin, Cobaye, Porc, Hamster, Gibbon, Gorilla

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Connexin 43/GJA1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Connexin 43/GJA1 anticorps

Épitope: C-Term

Specificité: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogène: GJA1 antibody was raised against a peptide located in the C-Terminal domain of GJA1 (Human).

Information d'application

Indications d'application: GJA1 antibody can be used in ELISA, Western Blot starting at 1 - 2 μg/mL, immunohistochemistry starting at 10 μg/mL, immunocytochemistry, immunoprecipitation starting at 1 - 2 μg/mL, and flow cytometry starting at 1 - 2 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-80 °C

Stockage commentaire: GJA1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Détails sur Connexin 43/GJA1

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Autre désignation: GJA1

Sujet: Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.

ID gène: 2697

UniProt: P17302

Pathways: Signalisation MAPK, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization