Integrin beta 2 anticorps (AA 534-546)

N° du produit ABIN2469881

L’anticorps anti-Integrin beta 2 Monoclonal Souris est utilisé pour la détection de Integrin beta 2 dans des échantillons de Humain. Il a été validé pour FACS, WB, IP et IHC.

Aperçu rapide pour Integrin beta 2 anticorps (AA 534-546) (ABIN2469881)

Antigène: Integrin beta 2 (ITGB2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 2 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Clone: MEM-48

Détail du produit anti-Integrin beta 2 anticorps

Épitope: AA 534-546

Specificité: Recongizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit, beta2 integrin).

Purification: Protein A Column

Immunogène: Integrin beta 2 monoclonal antibody was raised against Integrin beta 2 (Human).

Isotype: IgG1

Information d'application

Indications d'application: Integrin beta 2 antibody can be used in ELISA starting at 1:100000, Western Blot starting at 1:1000 - 1:10000, and immunohistochemistry starting at 5 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 15 mM sodium azide, approx., pH 7.4.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Integrin beta 2 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.

Détails sur Integrin beta 2

Antigène: Integrin beta 2 (ITGB2)

Autre désignation: Integrin beta 2

Sujet: CD18 is a 90-95 kDa type I transmembrane protein expressed on all leukocytes. The ITGB2 protein product is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

ID gène: 3689

UniProt: P05107

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation