CXCR4 anticorps

N° du produit ABIN2470068

Cet anticorps anti-CXCR4 Monoclonal Souris (Clone 12G5) (ABIN2470068) détecte spécifiquement CXCR4 dans IHC, FACS et IF. L’anticorps est réactif avec des échantillons de Humain, Singe, Babouin et Chimpanzé.

Aperçu rapide pour CXCR4 anticorps (ABIN2470068)

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reactivité: Humain, Singe, Babouin, Chimpanzé

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CXCR4 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 12G5

Détail du produit anti-CXCR4 anticorps

Purification: Affinity Chromatography

Isotype: IgG2a

Information d'application

Indications d'application: CXCR4 antibody can be used in immunohistochemistry starting at 10 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.2, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze thaw cycles

Stock: 4 °C

Stockage commentaire: Store CXCR4 antibody at 4 °C, Avoid Freezing

Détails sur CXCR4

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Autre désignation: CXCR4

Sujet: CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.

ID gène: 7852

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events