Cyclin A1 anticorps (full length)

N° du produit ABIN2470210

Détail du produit anti-Cyclin A1 anticorps

Antigène: Cyclin A1 (CCNA1)

Épitope: full length

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin A1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Purification: Delipidation and Defibrination

Immunogène: Full length synthetic polypeptide corresponding to the human gene sequence.

Information d'application

Indications d'application: Cyclin A1 antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01 % Sodium azide

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store Cyclin A1 antibody at 4 °C or -20 °C.

Détails sur Cyclin A1

Antigène: Cyclin A1 (CCNA1)

Autre désignation: Cyclin A1 (CCNA1 Produits)

Synonymes: anticorps fd14f08, anticorps wu:fd14f08, anticorps wu:fi20d12, anticorps zgc:111869, anticorps MGC81965, anticorps cyclin-A1, anticorps CCNA1, anticorps MGC132235, anticorps cyclin-A1-2, anticorps Cyclin-A1, anticorps ccna1, anticorps cyclin A1, anticorps cyclin A1 L homeolog, anticorps CYCLIN A1;2, anticorps cyclin A1 S homeolog, anticorps CCNA1, anticorps ccna1, anticorps ccna1.L, anticorps CYCA1;2, anticorps Ccna1, anticorps ccna1.S

Sujet: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

ID gène: 8900

UniProt: P78396

Pathways: Apoptose, Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA