SLIT1 anticorps (AA 155-173)

N° du produit ABIN2470344

Cet anticorps anti-SLIT1 est un anticorps Lapin Polyclonal détectant SLIT1 dans WB, IHC, ELISA et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SLIT1 anticorps (AA 155-173) (ABIN2470344)

Antigène: SLIT1 (Slit Homolog 1 (SLIT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLIT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-SLIT1 anticorps

Épitope: AA 155-173

Purification: Immunoaffinity Chromatography

Immunogène: Slit Homolog 1 antibody was raised against amino acids 155 - 173 of Slit Homolog 1 (Mouse).

Information d'application

Indications d'application: Slit Homolog 1 antibody can be used in Western Blot, and immunohistochemistry starting at 20 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store Slit Homolog 1 antibody at 4 °C or -20 °C.

Détails sur SLIT1

Antigène: SLIT1 (Slit Homolog 1 (SLIT1))

Autre désignation: Slit Homolog 1

Sujet: SLIT-1 (also known as KIAA0813, MEGF4, multiple epidermal growth factor-like domains 4 and Slit homolog 1 protein) is a Slit protein. This protein is a ligand for the Roundabout (Robo) receptors and acts as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. In situ hybridization studies indicated that the rat SLIT-1 mRNA was specifically expressed in the neurons of fetal and adult forebrains. This data suggests that the SLIT genes form an evolutionarily conserved group in vertebrates and invertebrates, and that the mammalian SLIT proteins may participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions. Alternative splicing isoforms have been identified for Slit1 protein.

ID gène: 6585

UniProt: O75093

Pathways: Regulation of Cell Size