KIT anticorps (PE)

N° du produit ABIN2567119

Cet anticorps anti-KIT est un anticorps Souris Monoclonal détectant KIT dans FACS. Adapté pour Humain.

Aperçu rapide pour KIT anticorps (PE) (ABIN2567119)

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KIT est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: YB5-B8

Détail du produit anti-KIT anticorps (PE)

Specificité: The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDA receptor for stem cell factor (SCF) or steel factor.

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Stock: 4 °C

Stockage commentaire: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Détails sur KIT

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Autre désignation: CD117

Sujet: The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDA receptor for stem cell factor (SCF) or steel factor. This tyrosine kinase protein is expressed mainly on hematopoietic progenitor, mast cells, acute myeloid leukemia cells (AML). CD117 activation promotes proliferation and cell differentiation on these cell subtypes. A lack or defect of SCF can lead to a decrease in number of hematopoietic progenitor cells and severe anemia.

ID gène: 3815

UniProt: P10721

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity