ITGAL anticorps
Aperçu rapide pour ITGAL anticorps (ABIN2567121)
Antigène
Voir toutes ITGAL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein.
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Purification
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
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Isotype
- IgG2a kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate-buffered aqueous solution, ph7.2.
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Stock
- 4 °C
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Stockage commentaire
- The product should be stored undiluted at 4°C. Do not freeze.
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- ITGAL (Integrin alpha-L (ITGAL))
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Autre désignation
- CD11a
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Sujet
- The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The M17/4 antibody blocks many of the LFA-1 mediated cell interaction and in vivo it prolongs allograft survival, inhibits the autoimmune response, and reduces graft versus host reactions.
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ID gène
- 16408
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UniProt
- P24063
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Pathways
- Activated T Cell Proliferation, Integrin Complex
Antigène
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