CD3 anticorps

N° du produit ABIN2567500

Cet anticorps anti-CD3 est un anticorps Souris Monoclonal détectant CD3 dans FACS, IHC et Func. Adapté pour Humain.

Aperçu rapide pour CD3 anticorps (ABIN2567500)

Antigène: CD3

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)

Clone: OKT3

Détail du produit anti-CD3 anticorps

Specificité: The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex.

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Stock: 4 °C

Stockage commentaire: The product should be stored undiluted at 4°C. Do not freeze.

Détails sur CD3

Antigène: CD3

Autre désignation: CD3

Sujet: The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.

ID gène: 916

UniProt: P07766

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway