CD3 anticorps (FITC)
Aperçu rapide pour CD3 anticorps (FITC) (ABIN2567522)
Antigène
Voir toutes CD3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex.
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Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Isotype
- IgG1 kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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Stock
- 4 °C
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Stockage commentaire
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- CD3
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Autre désignation
- CD3
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Sujet
- The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3ε. The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.
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ID gène
- 916
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UniProt
- P07766
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Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
Antigène
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