CD4 anticorps (violetFluor™ 450)

N° du produit ABIN2567651

Cet anticorps Souris Monoclonal détecte spécifiquement CD4 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CD4 anticorps (violetFluor™ 450) (ABIN2567651)

Antigène: CD4

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD4 est conjugé à/à la violetFluor™ 450

Application: Flow Cytometry (FACS)

Clone: RPA-T4

Détail du produit anti-CD4 anticorps (violetFluor™ 450)

Specificité: The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV).

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Stock: 4 °C

Stockage commentaire: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Détails sur CD4

Antigène: CD4

Autre désignation: CD4

Sujet: The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation, together with the MHC class II. The RPA-T4 antibody is capable of blocking HIV binding and inhibiting syncytium formation, by binding to the D1 domain of the CD4 antigen. The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

ID gène: 920

UniProt: P01730

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events