FAS anticorps
Aperçu rapide pour FAS anticorps (ABIN2568063)
Antigène
Voir toutes FAS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis.
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Purification
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
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Isotype
- IgM kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate-buffered aqueous solution, ph7.2.
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Stock
- 4 °C
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Stockage commentaire
- The product should be stored undiluted at 4°C. Do not freeze.
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- FAS (TNF Receptor Superfamily, Member 6 (FAS))
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Autre désignation
- CD95
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Sujet
- The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis. It is expressed on fibroblasts, monocytes, lymphocytes, and neutrophils. CD95 induces apoptosis after binding with CD178 or Fas ligand and the EOS9.1 antibody is reported to be used for inducing apoptosis in Fas-positive cells.
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ID gène
- 355
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UniProt
- P25445
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Pathways
- Signalisation p53, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
Antigène
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