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Interferon gamma anticorps

Cet anticorps anti-Interferon gamma est un anticorps Rat Monoclonal détectant Interferon gamma dans ELISA, IHC, FACS, IF et Func. Adapté pour Souris.
N° du produit ABIN2568205

Aperçu rapide pour Interferon gamma anticorps (ABIN2568205)

Antigène

Voir toutes Interferon gamma (IFNG) Anticorps
Interferon gamma (IFNG)

Reactivité

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Souris

Hôte

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Rat

Clonalité

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Monoclonal

Conjugué

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Cet anticorp Interferon gamma est non-conjugé

Application

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ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Clone

XMG1-2
  • Specificité

    The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties.

    Purification

    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

    Isotype

    IgG1 kappa
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    2 mg/mL

    Buffer

    Phosphate-buffered aqueous solution, ph7.2.

    Stock

    4 °C

    Stockage commentaire

    The product should be stored undiluted at 4°C. Do not freeze.
  • Antigène

    Interferon gamma (IFNG)

    Autre désignation

    IFN gamma

    Sujet

    The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-γ plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. IFN- γ is the primary cytokine that defines Th-1 cells.The biological activity of IFN-γ is not affected by glycosylation.

    ID gène

    15978

    UniProt

    P01580

    Pathways

    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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