CD14 anticorps (FITC)

N° du produit ABIN2618363

Cet anticorps Souris Monoclonal détecte spécifiquement CD14 dans FACS et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour CD14 anticorps (FITC) (ABIN2618363)

Antigène: CD14

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est conjugé à/à la FITC

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: MEM18

Détail du produit anti-CD14 anticorps (FITC)

Purification: Purified

Isotype: IgG1

Information d'application

Indications d'application: Approved: Flo, IF

Usage: CD14 is a GPI-anchored molecule expressed by virtually all human monocytes and macrophages and - to a lesser degree - granulocytes. CD14 together with Toll-like receptor 4 and MD-2 forms the LPS-receptor complex that recognizes and signals the presence of LPS. While CD14 has no signaling structure its main role seems to be the binding of LPS.

The MEM18 antibody permits the identification and enumeration of leukocytes using flow cytometry. MEM18 has been also used for functional studies since this antibody blocks the interaction of LPS with CD14 on monocytes. Results must be put within the context of other diagnostic tests as well as the clinical history of the patient by a certified professional before final interpretation. Analyses performed with this antibody should be paralleled by positive and negative controls. If unexpected results are obtained which cannot be attributed to differences in laboratory procedures, please contact us. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 1 % BSA, 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze. Protect from light.

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: Name/Gene ID: CD14

Synonyms: CD14, CD14 Molecule, CD14 antigen

ID gène: 929

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades