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IGF1R anticorps (AA 1353-1367)

Cet anticorps anti-IGF1R est un anticorps Lapin Polyclonal détectant IGF1R dans WB, IHC et IHC (p). Adapté pour Humain, Souris et Rat.
N° du produit ABIN2622640

Aperçu rapide pour IGF1R anticorps (AA 1353-1367) (ABIN2622640)

Antigène

Voir toutes IGF1R Anticorps
IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Reactivité

  • 193
  • 109
  • 94
  • 16
  • 8
  • 8
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 176
  • 35
  • 2
  • 2
  • 1
Lapin

Clonalité

  • 176
  • 38
  • 1
Polyclonal

Conjugué

  • 133
  • 9
  • 8
  • 8
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
Cet anticorp IGF1R est non-conjugé

Application

  • 135
  • 74
  • 66
  • 64
  • 31
  • 27
  • 22
  • 14
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  • 5
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 23
    • 23
    • 19
    • 14
    • 12
    • 12
    • 12
    • 10
    • 6
    • 6
    • 6
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    • 5
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    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1353-1367

    Specificité

    Found as a hybrid receptor with INSR in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Expressed in a variety of tissues. Overexpressed in tumors, including melanomas, cancers of the colon, pancreas prostate and kidney. .

    Réactivité croisée (Details)

    No cross reactivity with other proteins.

    Purification

    Immunogen affinity purified

    Immunogène

    A synthetic peptide corresponding to a sequence at the C-terminus of human IGF1 Receptor(1353-1367aa RKNERALPLPQSSTC), different from the related rat and mouse sequences by one amino acid.

    Isotype

    IgG
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Reconstitution

    Distilled water

    Concentration

    Lot specific

    Buffer

    Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

    Agent conservateur

    Sodium azide, Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
  • Antigène

    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

    Autre désignation

    IGF1R / IGF1 Receptor

    Sujet

    Name/Gene ID: IGF1R
    Subfamily: Insulin receptor
    Family: Protein Kinase

    Synonyms: IGF1R, CD221 antigen, CD221, IGF1 Receptor, IGFR, IGF-I receptor, Soluble IGF1R variant 1, Soluble IGF1R variant 2, Type 1 IGF receptor, IGFIR, JTK13

    ID gène

    3480

    Pathways

    Signalisation RTK, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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