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NLRP3 anticorps (AA 12-31)

L’anticorps Lapin Polyclonal anti-NLRP3 a été validé pour WB, IHC et IHC (p). Il convient pour détecter NLRP3 dans des échantillons de Humain et Singe.
N° du produit ABIN2625930

Aperçu rapide pour NLRP3 anticorps (AA 12-31) (ABIN2625930)

Antigène

Voir toutes NLRP3 Anticorps
NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

Reactivité

  • 90
  • 44
  • 30
  • 14
  • 5
  • 1
  • 1
  • 1
  • 1
Humain, Singe

Hôte

  • 81
  • 17
  • 2
  • 1
Lapin

Clonalité

  • 76
  • 25
Polyclonal

Conjugué

  • 53
  • 9
  • 7
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp NLRP3 est non-conjugé

Application

  • 56
  • 40
  • 19
  • 15
  • 15
  • 10
  • 10
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 12-31

    Specificité

    Expressed in blood leukocytes. Strongly expressed in polymorphonuclear cells and osteoblasts. Undetectable or expressed at a lower magnitude in B- and T-lymphoblasts, respectively. High level of expression detected in chondrocytes. Detected in non-keratinizing epithelia of oropharynx, esophagus and ectocervix and in the urothelial layer of the bladder. .

    Réactivité croisée (Details)

    No cross reactivity with other proteins.

    Purification

    Immunogen affinity purified

    Immunogène

    A synthetic peptide corresponding to a sequence at the N-terminus of human CIAS1(12-31aa RYLEDLEDVDLKKFKMHLED), different from the related rat and mouse sequences by one amino acid.

    Isotype

    IgG
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Reconstitution

    Distilled water

    Concentration

    Lot specific

    Buffer

    Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

    Agent conservateur

    Sodium azide, Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
  • Antigène

    NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

    Autre désignation

    NALP3 / NLRP3

    Sujet

    Name/Gene ID: NLRP3

    Synonyms: NLRP3, AGTAVPRL, AII, C1orf7, Caterpiller protein 1.1, Cryopyrin, FCAS, FCU, PYPAF1, NALP3, CIAS1, CLR1.1, MWS

    ID gène

    114548

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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