NAPSA anticorps (N-Term)

N° du produit ABIN263986

Cet anticorps Souris Monoclonal détecte spécifiquement NAPSA dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour NAPSA anticorps (N-Term) (ABIN263986)

Antigène: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NAPSA est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KCG1-1

Détail du produit anti-NAPSA anticorps

Épitope: N-Term

Specificité: Napsin A and TTF-1 reactivities were determined immunohistochemically on formalin-fixed paraffin embedded cell blocks from 50 pleural effusion (5 mesotheliomas, 10 mesothelial proliferations, 12 pulmonary, and 23 nonpulmonary metastases). TTF-1 and Napsin A were positive in 8/12 and 10/12 pulmonary adenocarcinomas, respectively. The specificity of this antibody for primary lung adenocarcinoma is 47 out of 58 (81 %), primary lesions were positive. This antibody may be a useful tool as a tumor marker for primary lung adenocarcinoma.

Attributs du produit: Synonyms: NAPSA, NAP1, Napsin-1, Aspartyl protease 4, TA01/TA02

Purification: Purified

Immunogène: Synthetic peptide from N terminus of Human Napsin A

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: Use at 1/50-1/100 dilution in an ABC method(30 minutes at room temperature). However, depending upon the fixation conditions andthe staining system employed, optimal incubation should be determined by the end user. Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Lung Adenocarcinoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur NAPSA

Antigène: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Autre désignation: Napsin-A

Sujet: Napsin is found in two isoforms, A and B, with highly homologous gene sequences. Napsin A has a molecular weight of 35.0 kDa and is also known as TA02. Napsin A is an aspartic proteinase which is expressed in the lung and involved in processing surfactant protein B (SP-B). It is also expressed in the kidney.Synonyms: Aspartyl protease 4, NAP1, NAPSA, Napsin-1, TA01/TA02

ID gène: 9476

UniProt: O96009

Pathways: Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis