CDK4 anticorps

N° du produit ABIN264334

Cet anticorps Souris Monoclonal détecte spécifiquement CDK4 dans WB, IF et IP. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CDK4 anticorps (ABIN264334)

Antigène: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDK4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: DCS-31-2

Détail du produit anti-CDK4 anticorps

Attributs du produit: Synonyms: PSK-J3, Cell division protein kinase 4, Cyclin-dependent kinase 4

Purification: Purified

Immunogène: Recombinant cdk 4 protein recognizing a 34kD protein.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot. Immunoprecipitation (unbound cdk4 only). Immunofluorescense.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.08 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur CDK4

Antigène: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Autre désignation: CDK4

Sujet: Cdk4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. Cdk4 is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1/S phase, which is controlled by the regulatory subunits D type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). The mutations in this gene as well as its related proteins including D type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Two alternatively spliced variants, and multiple polyadenylation sites of this gene have been reported.Synonyms: Cell division protein kinase 4, Cyclin-dependent kinase 4, PSK-J3

ID gène: 1019

UniProt: P11802

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, Regulation of Cell Size