DLL1 anticorps
Aperçu rapide pour DLL1 anticorps (ABIN2656778)
Antigène
Voir toutes DLL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
- The Notch receptors and their ligands are highly conserved from invertebrates to mammals. The Delta-like 1 (DLL1) is one of the four or five Notch ligands identified. The binding to Notch receptor results in the proteolysis of Notch and movement of intracellular portion of Notch into the nucleus.This translocation triggers a series of signaling process. Delta-like 1 is reported to be essential for the maintenance of marginal zone B cells in normal mice, and engagement of Notch 1 by DLL1 promotes differentiation of B lymphocytes to antibody-secreting cells.
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Purification
- The antibody was purified by affinity chromatography.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store undiluted between 2°C and 8°C. Do not freeze.
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- DLL1 (delta-Like 1 (DLL1))
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Autre désignation
- DLL1
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Pathways
- Signalisation Notch, Stem Cell Maintenance
Antigène
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