CD44 anticorps (Alexa Fluor 594)

N° du produit ABIN2656833

Cet anticorps Rat Monoclonal détecte spécifiquement CD44 dans FACS. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour CD44 anticorps (Alexa Fluor 594) (ABIN2656833)

Antigène: CD44

Reactivité: Humain, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est conjugé à/à la Alexa Fluor 594

Application: Flow Cytometry (FACS)

Clone: IM7

Détail du produit anti-CD44 anticorps (Alexa Fluor 594)

Réactivité croisée: Chimpanzé, Babouin, Cynomolgus, Macaque rhésus, Squirrel Monkey (Saimiri spec.), Cheval, Boeuf (Vache), Porc, Chien, Chat

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594 under optimal conditions. The solution is free of unconjugated Alexa Fluor® 594.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling