SIGLEC5 anticorps (APC)

N° du produit ABIN2656969

L’anticorps Souris Monoclonal anti-SIGLEC5 a été validé pour ELISA. Il convient pour détecter SIGLEC5 dans des échantillons de Humain.

Aperçu rapide pour SIGLEC5 anticorps (APC) (ABIN2656969)

Antigène: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIGLEC5 est conjugé à/à la APC

Application: ELISA

Clone: 1A5

Détail du produit anti-SIGLEC5 anticorps (APC)

Réactivité croisée: Chimpanzé, Bonobo, Gorilla

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur SIGLEC5

Antigène: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Autre désignation: CD170

Sujet: CD170, also known as Siglec-5, is a single pass transmembrane protein member of the immunoglobulin superfamily. On the cell surface, CD170 forms a 140 kD dimer. The cytoplasmic domain of Siglec-5 contains two ITIM motifs that recruit the tyrosine-phosphatases SHP-1 and SHP-2 after tyrosine-phosphorylation, which in turn results in the inhibition of cell signaling. Siglec-5 is expressed by granulocytes, monocytes/macrophages, subsets of lymphocytes, and a subset of activated dendritic cells. Siglec-5 binds α2,3- and α2,6-linked sialic acid as well as glycophorin A, and is involved in cell adhesion.