CXCR4 anticorps (Alexa Fluor 647)

N° du produit ABIN2657141

Cet anticorps anti-CXCR4 Monoclonal Rat conjugué à Alexa Fluor 647 (Clone L276F12) (ABIN2657141) détecte spécifiquement CXCR4 dans FACS. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour CXCR4 anticorps (Alexa Fluor 647) (ABIN2657141)

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CXCR4 est conjugé à/à la Alexa Fluor 647

Application: Flow Cytometry (FACS)

Clone: L276F12

Détail du produit anti-CXCR4 anticorps (Alexa Fluor 647)

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur CXCR4

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Autre désignation: CD184

Sujet: CD184, also known as CXCR4, is a member of the G protein coupled receptor family that binds CXCL12 (SDF1). CXCR4 and CXCL12 play an important role in immune and inflammatory responses through the regulation of cell migration and growth. CXCR4 plays a crucial role in the pathogenesis of several autoimmune diseases such as atherosclerosis, rheumatoid arthritis, and wound healing. In addition, CXCR4 is the cofactor for fusion and entry of the T cell-tropic form of HIV-1.

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events