INPP5D anticorps (Alexa Fluor 647)

N° du produit ABIN2657226

Cet anticorps Souris Monoclonal détecte spécifiquement INPP5D dans FACS et IHC. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour INPP5D anticorps (Alexa Fluor 647) (ABIN2657226)

Antigène: INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp INPP5D est conjugé à/à la Alexa Fluor 647

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Clone: P1C1-A5

Détail du produit anti-INPP5D anticorps (Alexa Fluor 647)

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur INPP5D

Antigène: INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

Autre désignation: SHIP-1

Sujet: SH2-containing inositol phosphatase 1 (SHIP1) is a hematopoietic phosphatase that hydrolyzes key signaling lipid PI(3,4,5)P(3) to PI(3,4)P(2). SHIP-1 is located in the cytoplasm and is recruited to the cell surface upon receptor ligation. It plays critical roles in hematopoietic cell proliferation, activation, differentiation, and survival by regulating PI3K and Akt pathways. Aberrant regulation of PI3K signaling can induce autoimmune diseases and cancer formation.

Pathways: TCR Signaling, BCR Signaling, L'effet Warburg