CD14 anticorps (Alexa Fluor 647)

N° du produit ABIN2657631

Cet anticorps Souris Monoclonal détecte spécifiquement CD14 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CD14 anticorps (Alexa Fluor 647) (ABIN2657631)

Antigène: CD14

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est conjugé à/à la Alexa Fluor 647

Application: Flow Cytometry (FACS)

Clone: M5E2

Détail du produit anti-CD14 anticorps (Alexa Fluor 647)

Réactivité croisée: Chimpanzé, Cynomolgus, Macaque rhésus, Capuchin Monkey, Saguinus oedipus, Pigtailed Macaque, Marmoset, Squirrel Monkey (Saimiri spec.), Boeuf (Vache), Porc, Chien

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades