JAG1 anticorps (APC)

N° du produit ABIN2658199

Détail du produit anti-JAG1 anticorps (APC)

Antigène: JAG1 (Jagged 1 (JAG1))

Reactivité: Souris

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp JAG1 est conjugé à/à la APC

Application: Cytometry by Time of Flight (CyTOF), ELISA (Capture)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: HMJ1-29

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur JAG1

Antigène: JAG1 (Jagged 1 (JAG1))

Autre désignation: CD339 (JAG1 Produits)

Synonymes: anticorps AGS, anticorps AHD, anticorps AWS, anticorps CD339, anticorps HJ1, anticorps JAGL1, anticorps ABE2, anticorps Gsfabe2, anticorps Htu, anticorps Ozz, anticorps Ser-1, anticorps JAG1, anticorps jag3, anticorps cb243, anticorps jag1, anticorps sb:cb243, anticorps serrateC, anticorps jagged1, anticorps serrate, anticorps serrate-1, anticorps x-serrate-1, anticorps jagged 1, anticorps jagged 1b, anticorps jagged 1a, anticorps jagged 1 L homeolog, anticorps JAG1, anticorps Jag1, anticorps jag1, anticorps jag1b, anticorps jag1a, anticorps jag1.L

Sujet: CD339, also known as Jagged 1, is a 135 kD type 1 transmembrane protein, with one DSL (Delta, Serrate, LagZ) domain, fifteen EGF-like domains, and one cysteine-rich region. Jagged 1 is expressed by many cell types including macrophages, subsets of dendritic cells, astrocytes, stromal, and epithelial cells. CD339 regulates cell fate decisions in various tissues, and has an important role in neurogenesis and development of the cardiovascular system. Studies suggest Jagged 1 is involved in Th2 polarization and Treg induction.

Pathways: Signalisation Notch, Stem Cell Maintenance