C5AR1 anticorps (APC)

N° du produit ABIN2658284

Cet anticorps anti-C5AR1 Monoclonal Rat conjugué à APC (Clone 20-70) (ABIN2658284) détecte spécifiquement C5AR1 dans ELISA (Detection). L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour C5AR1 anticorps (APC) (ABIN2658284)

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp C5AR1 est conjugé à/à la APC

Application: ELISA (Detection)

Clone: 20-70

Détail du produit anti-C5AR1 anticorps (APC)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur C5AR1

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Autre désignation: CD88

Sujet: CD88 is a single chain protein with seven membrane-spanning regions and a molecular weight of 43 kD. CD88 is expressed by neutrophils, eosinophils, and monocytes. There have been reports of CD88 expression in non-immune cells such as glial cells, cerebellar granule cells, cardiomyocytes, and vascular endothelial cells. CD88 is coupled to heterotrimeric G proteins such as Gi, and after C5a binding, the signal transduced by CD88 results in the activation of PLCβ, PI-3 kinase, and PLA2, among other molecules, resulting in chemotaxis, granule enzyme release, and superoxide anion production.

Pathways: Système du Complément