ITGA2 anticorps (APC)

N° du produit ABIN2658887

Cet anticorps anti-ITGA2 est un anticorps Rat Monoclonal détectant ITGA2 dans FACS. Adapté pour Souris.

Aperçu rapide pour ITGA2 anticorps (APC) (ABIN2658887)

Antigène: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA2 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: DX5

Détail du produit anti-ITGA2 anticorps (APC)

Purification: The solution is free of unconjugated APC and unconjugated antibody.

Isotype: IgM kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur ITGA2

Antigène: ITGA2 (Integrin alpha 2 (ITGA2))

Autre désignation: CD49b

Sujet: DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex