IFNAR1 anticorps (Biotin)

N° du produit ABIN2661195

Cet anticorps anti-IFNAR1 Monoclonal Souris conjugué à Biotin (Clone MAR1-5A3) (ABIN2661195) détecte spécifiquement IFNAR1 dans IHC et FACS. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour IFNAR1 anticorps (Biotin) (ABIN2661195)

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNAR1 est conjugé à/à la Biotin

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: MAR1-5A3

Détail du produit anti-IFNAR1 anticorps (Biotin)

Purification: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur IFNAR1

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Autre désignation: IFNAR-1

Sujet: IFNAR-1, the type I IFN receptor subunit 1, is coexpressed with IFNAR-2 on nearly all cells and make up the heterodimeric receptor complex that binds to all type I IFNs (IFN-α/β). Type I IFNs are a group of structurally and functionally related cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor, and autoimmune responses. Ligand binding to the IFN-α/β receptor complex leads to the tyrosine phosphorylation and activation of IFNAR-1-associated Tyk2 and IFNAR-2-associated Jak1 signal transductions.

Pathways: Signalistation JAK/STAT, Hepatitis C