EPH Receptor A2 anticorps (PE)
Aperçu rapide pour EPH Receptor A2 anticorps (PE) (ABIN2662716)
Antigène
Voir toutes EPH Receptor A2 (EPHA2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
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Isotype
- IgG2b kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from prolonged exposure to light. Do not freeze.
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Stock
- 4 °C
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Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- EPH Receptor A2 (EPHA2)
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Autre désignation
- EphA2
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Sujet
- Ephrin receptor A2 (EphA2), also known as Eck, is a 130 kD type I transmembrane glycoprotein which belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA2 is expressed on epithelial cells, keratinocytes, dendritic/Langerhans cells and melanocytes. It has also been observed in breast, cervical, ovarian, prostate, colon, skin and lung cancers. EphA2 is an oncoprotein which is an essential survival factor for many melanomas. EphA2 plays an important role in angiogenesis and tumor neovascularization through interaction with ephrin-A1, -A3, -A4 and -A5.
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Pathways
- Signalisation RTK
Antigène
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