CXCR7 anticorps (PE)

N° du produit ABIN2663672

Cet anticorps anti-CXCR7 est un anticorps Souris Monoclonal détectant CXCR7 dans FACS. Adapté pour Humain et Souris.

Aperçu rapide pour CXCR7 anticorps (PE) (ABIN2663672)

Antigène: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CXCR7 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: 8F11-M16

Détail du produit anti-CXCR7 anticorps (PE)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CXCR7

Antigène: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Autre désignation: CXCR7

Sujet: CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large protein family of G protein-coupled receptors (GPCR). CXCR7 binds with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, which regulates the trafficking and activation of leukocytes. It is also a co-receptor for the entry of HIV-1. Binding of ligand to CXCR7 induces proliferation and migration of immature neurons, glia and their precursors. CXCR7 expression occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendritic cells. Surface expression of CXCR7 was also reported to be on tumor cells, activated endothelial cells, fetal liver cells, and other cell types.

Pathways: Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling