IFNAR1 anticorps (PE)

N° du produit ABIN2663759

Détail du produit anti-IFNAR1 anticorps (PE)

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNAR1 est conjugé à/à la PE

Application: ELISA (Detection)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: MAR1-5A3

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur IFNAR1

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Autre désignation: IFNAR-1 (IFNAR1 Produits)

Synonymes: anticorps ifnar1, anticorps IFNAR1, anticorps CD118, anticorps Ifar, anticorps Ifnar, anticorps Ifrc, anticorps Infar, anticorps AVP, anticorps IFN-alpha-REC, anticorps IFNAR, anticorps IFNBR, anticorps IFRC, anticorps IFN-R-1, anticorps interferon alpha and beta receptor subunit 1, anticorps interferon-alpha/beta receptor alpha chain-like, anticorps interferon (alpha and beta) receptor 1, anticorps interferon alpha/beta receptor 1, anticorps IFNAR1, anticorps ifnar1, anticorps Ifnar1, anticorps LOC609830

Sujet: IFNAR-1, the type I IFN receptor subunit 1, is coexpressed with IFNAR-2 on nearly all cells and make up the heterodimeric receptor complex that binds to all type I IFNs (IFN-α/β). Type I IFNs are a group of structurally and functionally related cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor, and autoimmune responses. Ligand binding to the IFN-α/β receptor complex leads to the tyrosine phosphorylation and activation of IFNAR-1-associated Tyk2 and IFNAR-2-associated Jak1 signal transductions.

Pathways: Signalistation JAK/STAT, Hepatitis C