IL3RA anticorps

N° du produit ABIN2664180

Détail du produit anti-IL3RA anticorps

Antigène: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL3RA est non-conjugé

Application: Multiplex Assay (MA)

Réactivité croisée: Macaque rhésus

Purification: The antibody was purified by affinity chromatography.

Clone: 6H6

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur IL3RA

Antigène: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Autre désignation: CD123 (IL3RA Produits)

Synonymes: anticorps CD123, anticorps IL3R, anticorps IL3RAY, anticorps IL3RX, anticorps IL3RY, anticorps hIL-3Ra, anticorps CDw123, anticorps SUT-1, anticorps Cyrl, anticorps interleukin 3 receptor subunit alpha, anticorps interleukin 3 receptor, alpha chain, anticorps IL3RA, anticorps Il3ra

Sujet: CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity, when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.

Pathways: Signalistation JAK/STAT