CD14 anticorps

N° du produit ABIN2664217

L’anticorps Souris Monoclonal anti-CD14 a été validé pour FACS, IHC, IP, IF et CyTOF. Il convient pour détecter CD14 dans des échantillons de Humain.

Aperçu rapide pour CD14 anticorps (ABIN2664217)

Antigène: CD14

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Cytometry by Time of Flight (CyTOF)

Clone: M5E2

Détail du produit anti-CD14 anticorps

Réactivité croisée: Chimpanzé, Cynomolgus, Macaque rhésus, Capuchin Monkey, Saguinus oedipus, Pigtailed Macaque, Marmoset, Squirrel Monkey (Saimiri spec.), Boeuf (Vache), Porc, Chien

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades